In vitro biological screening of the stem of Desmodium elegans

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• 作者：Arshad Khan ; Rabia Usman ; Abdur Rauf ; Ming-Liang Wang ; Naveed Muhammad ; Akhatar Aman ; Taha Hussein Musa Tahir
• 关键词：Leguminosae ; Desmodium elegans ; Brine shrimp cytotoxicity ; Phytotoxic ; Insecticidal and antimicrobial activities
• 刊名：Asian Pacific Journal of Tropical Biomedicine
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：3
• 期：9
• 页码：711-715
• 全文大小：442 K

文摘

Objective

To explore the medicinal importance of the stem of Desmodium elegans, methanolic extract, and its different solvent fractions were evaluated for brine shrimp lethality, insecticidal and phytotoxicity, antifungal, and antibacterial activities.

Methods

The methanolic extract and its solvent fractions were tested for cytotoxic, phytotoxic, insecticidal, antifungal, and antibacterial effects using our previous published protocols.

Results

The methanolic, DCM, ethyl acetate and n-butanol fractions exhibited insecticidal effect against Callosobruchus analis and Rhyzopertha dominic. The methanolic extract, n-hexane, DCM ethyl acetate and n-butanol showed 75, 85, 85, 65 and 5 % phytotoxicity at the tested concentration of 500 ¦Ìg/mL respectively. The solvent fractions (DCM and ethyl acetate) were effective against F. solani (10 % and 20 % inhibition respectively). All the tested samples were devoid of cytotoxic and antibacterial effects.

Conclusion

It was concluded that this plant can be practiced for control of weeds and insects.