Leukocyte susceptibility and immune response against Vibrio parahaemolyticus in Totoaba macdonaldi
详细信息 查看全文
- 作者：Martha Reyes-Becerrila ; mreyes@cibnor.mx" class="auth_mail" title="E-mail the corresponding author ; Erika Alamilloa ; Luvia Sá ; nchez-Torresb ; Felipe Ascencio-Vallea ; Juan C. Perez-Urbiolaa ; Carlos Anguloa ; eangulo@cibnor.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：Totoaba ; Vibrio parahaemolyticus ; Cellular immune response ; Gene expression ; Phagocytic activity ; Apoptosis
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：65
- 期：Complete
- 页码：258-267
- 全文大小：1013 K
文摘
- •
Totoaba macdonaldi exposed to Vibrio parahaemolyticus infection showed IL-1β and IL-8 up-regulation in several tissues.
- •
In vitro, IL-1β and IL-8 genes in leukocytes exposed to V. parahaemolyticus were up-regulated.
- •
The mRNA IL-1β and IL-8 transcription levels were down-regulated in thymus leucocytes exposed to V. parahaemolyticus.
- •
Phagocytic and respiratory burst responses during in vitro V. parahaemolyticus stimulation were reduced.
- •
The survival of leukocytes exposed to V. parahaemolyticus was reduced, causing apoptosis and necrosis.