Secondary coenzyme Q10 deficiencies in oxidative phosphorylation (OXPHOS) and non-OXPHOS disorders
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- 作者：Delia Yuberoa ; Raquel Monteroa ; b ; Miguel A. Martí ; nb ; c ; Julio Montoyab ; d ; Antonia Ribesb ; e ; Manuela Grazinaf ; Eva Trevissong ; Juan Carlos Rodriguez-Aguilerab ; h ; Iain P. Hargreavesi ; Leonardo Salviatig ; Plá ; cido Navasb ; h ; Rafael Artucha ; b ; rartuch@hsjdbcn.org" class="auth_mail" title="E-mail the corresponding author ; CoQ deficiency study group
- 关键词：CoQ ; Coenzyme Q10 ; OXPHOS ; Mitochondrial oxidative phosphorylation ; mtDNA ; mitochondrial DNA ; nDNA ; nuclear DNA ; CS ; citrate synthase ; MRC ; mitochondrial respiratory chain enzymes
- 刊名：Mitochondrion
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：30
- 期：Complete
- 页码：51-58
- 全文大小：357 K
文摘
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Coenzyme Q10 deficiency is a common finding in oxidative phosphorylation disorders.
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Similar percentage of low Coenzyme Q10 values was detected in other diseases.
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Coenzyme Q10 deficiency can be an adaptive mechanism for mitochondrial homeostasis.