• 作者：Mar¨ªa Lida Santiago ; Mar¨ªa Renata Seisdedos ; Rodrigo Nicol¨¢s Garc¨ªa Salinas ; Anastasia Secco ; Lucila Marino Claverie ; Lorena Techera ; Lorena Takashima ; Pedro Aicardi ; Marco Antonio S ; i Rosales ; Elizabeth Knobel ; Sebasti¨¢n Juan Magri ; Antonio Carlos Catal¨¢n Pellet
• 关键词：Sí ; ndrome de Sj&ouml ; gren ; Biopsia de glá ; ndulas salivales menores ; Complicaciones
• 刊名：Reumatolog¨ªa Cl¨ªnica
• 出版年：2012
• 出版时间：September-October, 2012
• 年：2012
• 卷：8
• 期：5
• 页码：255-258
• 全文大小：167 K

Findings of specific antibodies and histopathology data are essential for the diagnosis of Sj?gren syndrome (SS). Although the minor salivary gland biopsy (MSGB) is technically simple, it needs to be performed in a medical institution to avoid complications.

Objective

To determine the frequency of complications and the usefulness of this technique.

Materials and methods

Patients who underwent a minor salivary gland biopsy for a possible diagnosis of SS at Rivadavia Hospital between October 2007 and May 2010 where included. The patients were seen a week and a month after the procedure for follow up.

Results

Frequency of acute complications (n = 186): 15 patients; 8.1 % , 95 % CI: 4.7-13.2 (Bleeding 7.5 % , syncope 3.2 % , hematoma 2.7 % . No accidents occurred). Medium term complications (n = 164): 16 patients: 9.75 % , 95 % CI: 5.9-15.6 (pain 7.32 % , inflammation 3.66 % , sensitivity disorders 3.05 % , granuloma 1.22 % ,). No infections or suture dehiscence occurred. Microscopic results: 154 biopsy reports were received: glandular 90.9 % , 95 % CI: 85-95 (typical, sialadenitis, grade III and IV infiltration).

Conclusions

MSGB has very low frequency of medium term and acute complications and it has high usefulness.