Electrochemical immunosensor for simultaneous determination of interleukin-1 beta and tumor necrosis factor alpha in serum and saliva using dual screen printed electrodes modified with functionalized double-walled carbon nanotubes

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• 作者：E. Sá ; nchez-Tirado^a ; C. Salvo^a ; A. Gonzá ; lez-Corté ; s^a ; P. Yá ; ñ ; ez-Sedeñ ; o^a ; ^{yseo@quim.ucm.es} ; F. Langa^b ; J.M. Pingarró ; n^a
• 关键词：Interleukin-1 beta ; Tumor necrosis factor-alpha ; Electrochemical immunosensor ; Multiplex ; Double-walled carbon nanotubes ; Saliva
• 刊名：Analytica Chimica Acta
• 出版年：2017
• 出版时间：22 March 2017
• 年：2017
• 卷：959
• 期：Complete
• 页码：66-73
• 全文大小：799 K
• 卷排序：959

文摘

Electrochemical immunosensor for simultaneous determination of IL-β1 and TNF-α cytokines. Oriented immobilization of capture antibodies and signal amplification. Improved analytical performance with respect to previous approaches and ELISA methods. Application to human serum and saliva.