Effects of a Novel Dietary Supplement on Indices of Muscle Injury and Articular GAG Release in Horses

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• 作者：Michael I. Lindinger^a ; ^{mi.lindinger@gmail.com} ; Jennifer M. MacNicol^a ; ^b ; Neil Karrow^b ; Wendy Pearson^a ; ^b
• 关键词：Exercise ; Oxidative stress ; Inflammation ; Nutraceutical ; Muscle enzymes ; Synovial fluid
• 刊名：Journal of Equine Veterinary Science
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：48
• 期：Complete
• 页码：52-60
• 全文大小：513 K
• 卷排序：48

文摘

We measured plasma and synovial fluid (from the intercarpal joint) markers of oxidative stress, inflammation and muscle damage before and after exercise, and before and after providing a supplement for 23 days. The supplement contained plant, mushroom and yeast products that have been shown to combat tissue oxidative stress and inflammation, and enhance immune function in animals. High-intensity exercise resulted in muscle injury and release of glycosaminoglycans (GAGs) from articular cartilage in the intercarpal joint. The supplement reduced the appearance of muscle enzymes in plasma and abolished the increase in synovial fluid GAGs after high-intensity exercise.