Ecabet sodium alleviates neomycin-induced hair cell damage
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- 作者：Yoon Chan Raha ; June Choia ; mednlaw@korea.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Myung Hoon Yooa ; Gunhwee Yuma ; Saemi Parka ; Kyoung Ho Oha ; Seung Hoon Leea ; Soon Young Kwona ; Seung Hyun Chob ; Suhyun Kimc ; Hae-Chul Parkc
- 关键词：Ecabet sodium ; Neomycin ; Hair cell ; Zebrafish ; Reactive oxygen species
- 刊名：Free Radical Biology and Medicine
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：89
- 期：Complete
- 页码：1176-1183
- 全文大小：4198 K
文摘
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The zebrafish is a useful model for evaluating hair cell damage caused by ototoxicity.
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Aminoglycoside administration significantly decreases the numbers of hair cells.
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Ecabet sodium protects against neomycin-induced hair cell loss.