The acute social defeat stress and nest-building test paradigm: A potential new method to screen drugs for depressive-like symptoms

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• 作者：Hikari Otabi^a ; Tatsuhiko Goto^a ; ^b ; ¹ ; Tsuyoshi Okayama^a ; ^b ; ^c ; Daisuke Kohari^a ; ^b ; ^c ; Atsushi Toyoda^a ; ^b ; ^c ; ^{atsushi.toyoda.0516@vc.ibaraki.ac.jp} ; ^{atsushi19690516@gmail.com}
• 关键词：Social defeat ; Behavior ; Depression ; Nest building
• 刊名：Behavioural Processes
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：135
• 期：Complete
• 页码：71-75
• 全文大小：550 K
• 卷排序：135

文摘

Acute social defeat stress delayed nesting behavior onset in mice. 5-HT2a receptor antagonist partially rescued the delay of nesting. SSRI deteriorated the delay of nesting behavior. 5-HT and 5-HT receptor may play an important role in nesting behavior.