23 different spleen protein species were able to discriminate between WT and CD38-KO mice upon Collagen-II immunization.
Among them, multiple serotransferrin (Tf) species, and a number of citrullinated protein species were identified.
μLC-TOF-MS revealed differences in the serum Tf glycosylation pattern between CD38-KO and WT mice with arthritis.
Data on Tf spots separated by 2-DE (i.e.: protein species) indicated differences in glycosylation related with their NeuGc content.