SIRT2 regulates insulin sensitivity in insulin resistant neuronal cells
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- 作者：Amita Arora ; Chinmoy Sankar Dey ; csdey@bioschool.iitd.ac.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：SIRT2 ; Insulin signaling ; Insulin resistance ; Neuronal cells
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：474
- 期：4
- 页码：747-752
- 全文大小：726 K
文摘
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Downregulation of SIRT2 improves insulin sensitivity in neuro-2a and SH-SY5Y cells.
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SIRT2 negatively regulates insulin resistance in neuronal cells.
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Study reveals a novel role of SIRT2 as a regulator of neuronal insulin resistance.