Reversible recovery of neuronal structures depends on the degree of neuronal damage after global cerebral ischemia in mice

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• 作者：Lirui Zhu ; Lei Wang ; Furong Ju ; Akbar Khan ; Xiaofeng Cheng ; Shengxiang Zhang ; ^{sxzhang@lzu.edu.cn}
• 关键词：Global cerebral ischemia ; Reperfusion ; Neuronal structures ; Recovery ; Two-photon imaging
• 刊名：Experimental Neurology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：289
• 期：Complete
• 页码：1-8
• 全文大小：2303 K
• 卷排序：289

文摘

Recovery of neuronal structures is critically dependent on the duration of ischemia. Ischemic damage progressively spreads to deeper dendritic shafts. The timeframe for recovery of dendritic structures is within 3–6 h after stroke onset. Reversible recovery of neurons may determine the therapeutic time window for stroke.