Level of serum thioredoxin and correlation with neurocognitive functions in patients with schizophrenia using clozapine and other atypical antipsychotics

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• 作者：Alper Bas^a ; ^{alperbas@outlook.com} ; Gozde Gultekin^b ; Said Incir^c ; Tuba Ocek Bas^a ; Murat Emul^b ; Alaatin Duran^b
• 关键词：TRX ; thioredoxin ; ELISA ; enzyme linked immune absorbent assay ; DSM-IV ; diagnostic and statistical manual of mental disorders ; PANSS ; positive and negative syndrome scale
• 刊名：Psychiatry Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：247
• 期：Complete
• 页码：84-89
• 全文大小：209 K
• 卷排序：247

文摘

Thioredoxin levels were higher in psychotic episodes and decreases after treatment; but still higher than healthy controls. Thioredoxin may not be used as a marker to detect the early stages of illness, but could be a marker for psychotic episodes. No correlation has been found between thioredoxin levels and treatment with clozapine or other atypical antipsychotics. The relationship between thioredoxin level and attention should be investigated in further researches.