Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function
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- 作者：Gabriel S. Bassia ; 1 ; Fernanda Brognarab ; 1 ; Jaci A. Castaniab ; Jhimmy Talbotc ; Thiago M. Cunhaa ; c ; Fernando Q. Cunhaa ; c ; Luis Ulload ; Alexandre Kanashiroc ; Daniel P. Martins Diasb ; Helio C. Salgadob ; hcsalgado@fmrp.usp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Baroreflex ; Inflammation ; Neuroimmunomodulation ; Sympathetic activity ; Parasympathetic activity
- 刊名：Brain, Behavior, and Immunity
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：49
- 期：Complete
- 页码：140-147
- 全文大小：1434 K
文摘
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First evidence that the baroreflex modulates the innate immune system.
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Activation of the baroreflex attenuates joint inflammation in experimental arthritis.
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The anti-inflammatory effect of the baroreflex modifies sympathetic function.
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A novel physiological neuronal network controlling local inflammation was revealed.