Differential Mitochondrial Requirements for Radially and Non-radially Migrating Cortical Neurons: Implications for Mitochondrial Disorders
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- 作者：Erika G. Lin-Hendel1 ; 2 ; Meagan J. McManus3 ; 4 ; Douglas C. Wallace3 ; 4 ; Stewart A. Anderson5 ; 7 ; sande@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author ; Jeffrey A. Golden6 ; 7 ; jagolden@partners.org" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 April 2016
- 年：2016
- 卷：15
- 期：2
- 页码：229-237
- 全文大小：3173 K
文摘
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Mitochondria in cortical interneurons are motile during migration
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Mitochondria are stationary in migrating cortical projection neurons
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Oxidative phosphorylation defects disrupt cortical interneuron migration
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Interneurons lose polarity when oxidative phosphorylation is perturbed