Duplication of neuropeptide Y and peptide YY in Nile tilapia Oreochromis niloticus and their roles in food intake regulation

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• 作者：Peipei Yan ; Jirong Jia ; Guokun Yang ; Dongfang Wang ; Caiyun Sun ; Wensheng Li ; ^{lsslws@mail.sysu.edu.cn}
• 关键词：Neuropeptide Y ; Peptide YY ; Food intake ; Nile tilapia
• 刊名：Peptides
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：88
• 期：Complete
• 页码：97-105
• 全文大小：1013 K
• 卷排序：88

文摘

NPYb had markedly lower expression than NPYa in the CNS. Feeding conditions affected hypothalamic NPYa expression, but not NPYb. PYYb mainly expressed in the gut, while PYYa only had low expression in the CNS. Hypothalamic PYYa and foregut PYYb expression were affected by feeding conditions. Synthetic NPYb stimulated food intake, while PYYb decreased food intake.