Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity

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• 作者：Hirofumi Morishita¹ ; ³ ; ^{hirofumi.morishita@mssm.edu} ; Manish Arora² ; ³ ; ^{manish.arora@mssm.edu}
• 关键词：teeth ; critical period ; brain plasticity ; biomarker
• 刊名：Trends in Neurosciences
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：40
• 期：1
• 页码：1-3
• 全文大小：852 K
• 卷排序：40

文摘

Developmental brain plasticity involves complex, time-dependent dynamic molecular interactions that cannot be observed directly in humans. We propose that the shared evolutionary homology of teeth and the neurosensory system, and the archival nature of dentine microstructure, allows the development of ‘biologic hard drives’ that can characterize perinatal temporal dynamics in neuroplasticity.