Macrophage migration inhibitory factor as a novel cerebrospinal fluid marker for neurosyphilis among HIV-negative patients

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• 作者：Li-Rong Lin^a ; ^c ; ¹ ; Dan-Hong Lin^b ; ¹ ; Man-Li Tong^a ; ¹ ; Li-Li Liu^a ; Jin-Yi Fan^a ; Xiao-Zhen Zhu^a ; Kun Gao^a ; Mei-Jun Chen^a ; Wei-Hong Zheng^a ; Hui-Lin Zhang^a ; Shu-Lian Li^d ; Hui-Ling Lin^d ; Zhi-Feng Lin^d ; Jian-Jun Niu^a ; ^c ; ^{niujianjun211@xmu.edu.cn} ; Tian-Ci Yang^a ; ^c ; ^{yangtianci@xmu.edu.cn}
• 关键词：Macrophage migration inhibitory factor ; Treponema pallidum ; Neurosyphilis ; Diagnosis ; Marker
• 刊名：Clinica Chimica Acta
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：463
• 期：Complete
• 页码：103-108
• 全文大小：373 K
• 卷排序：463

文摘

CSF MIF were higher in neurosyphilis patients than syphilis/non-neurosyphilis patients. CSF MIF concentrations can be used as a novel cerebrospinal fluid marker to establish or exclude a diagnosis of neurosyphilis. The sensitivity of CSF MIF was higher than that of CSF pleocytosis and CSF increased protein in diagnosis of probable neurosyphilis.