Drosophila Vision Depends on Carcinine Uptake by an Organic Cation Transporter
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- 作者：Ratna Chaturvedi1 ; Zhuo Luan1 ; Peiyi Guo1 ; Hong-Sheng Li1 ; hong-sheng.li@umassmed.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：vision ; neurotransmitter recycling ; histamine ; membrane transporter
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：8 March 2016
- 年：2016
- 卷：14
- 期：9
- 页码：2076-2083
- 全文大小：2321 K
文摘
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CarT mediates the uptake of carcinine in transfected S2 cells
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CarT is required for carcinine trafficking and maintenance of eye histamine levels
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The expression of CarT in photoreceptors is essential for fly visual transmission
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Loss of CarT in the fly photoreceptor causes blindness