Neurotrophins role in depressive symptoms and executive function performance: Association analysis of NRN1 gene and its interaction with BDNF gene in a non-clinical sample

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• 作者：C. Prats^a ; ^b ; ^f ; B. Arias^a ; ^b ; ^f ; G. Ortet^b ; ^c ; M.I. Ibá ; ñ ; ez^b ; ^c ; J. Moya^b ; ^d ; E. Pomarol-Clotet^b ; ^e ; L. Fañ ; aná ; s^a ; ^b ; ^f ; M. Fatjó ; -Vilas^a ; ^b ; ^e ; ^f ; ^{mar.fatjovilas@ub.edu} ; ^{mfatjo-vilas@fidmag.com}
• 关键词：Depressive symptoms ; Executive function ; NRN1 ; BDNF ; Gene-gene interaction ; General population
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：211
• 期：Complete
• 页码：92-98
• 全文大小：413 K
• 卷排序：211

文摘

NRN1 gene is associated with depressive symptoms in a general population based sample. The role of NRN1 on depressive symptoms is modulated by BDNF gene. Non-clinical samples provide new insights on the genetic basis of mental disorders.