Consequences of low or moderate prenatal ethanol exposures during gastrulation or neurulation for open field activity and emotionality in mice
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- 作者：Uta B. Schambraa ; schambra@etsu.edu" class="auth_mail" title="E-mail the corresponding author ; Kevin Nunleya ; 1 ; Theresa A. Harrisona ; C. Nicole Lewisb
- 刊名：Neurotoxicology and Teratology
- 出版年：2016
- 出版时间：September-October 2016
- 年：2016
- 卷：57
- 期：Complete
- 页码：39-53
- 全文大小：1289 K
文摘
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Mice were acutely exposed to ethanol during gastrulation or neurulation.
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Ethanol levels were equivalent to 1–2 alcoholic drinks.
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Juvenile mice showed modest deficits (decreased activity, increased emotionality).
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Exposure during gastrulation had greater effect than during neurulation.
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Limited effects on behavior persisted into adulthood.