Antiproliferative activity of buttermilk lipid fractions isolated using food grade and non-food grade solvents on human cancer cell lines
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- 作者：Pilar Castro-Gó ; meza ; Luis M. Rodrí ; guez-Alcalá ; a ; Karin M. Monteirob ; c ; Ana L.T.G. Ruizb ; Joã ; o E. Carvalhob ; d ; Javier Fontechaa ; j.fontecha@csic.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：MFGM ; milk fat globule membrane ; TAG ; triacylglycerols ; DAG ; diacylglycerols ; CHOL ; cholesterol ; PLs ; polar lipids ; PI ; phosphatidylinositol ; PS ; phosphatidylserine ; PE ; phosphatidylethanolamine ; PC ; phosphatidylcholine ; SM ; sphingomyelin ; BM ; buttermilk ; FG ; food grade method ; NFG ; non-food grade method ; FBS ; fetal bovine serum ; FC ; flash chromatography ; ELSD ; evaporative light scattering detector ; TGI ; total growth inhibition ; GI50 ; 50% growth inhibition
- 刊名：Food Chemistry
- 出版年：2016
- 出版时间：1 December 2016
- 年：2016
- 卷：212
- 期：Complete
- 页码：695-702
- 全文大小：846 K
文摘
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Buttermilk is a source of MFGM polar lipids that may contribute as a nutraceutical.
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Food grade solvent lipid extract show antiproliferative activity on cancer cells.
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Phospho- and sphingolipids seems crucial for the antiproliferative activity.
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Lipid extracts from buttermilk could be a valuable functional food ingredient.