The immunomodulatory role of the hypothalamus-pituitary-gonad axis: Proximate mechanism for reproduction-immune trade offs?
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- 作者：Helmut Segnera ; helmut.segner@vetsuisse.unibe.ch" class="auth_mail" title="E-mail the corresponding author ; B.M. Lidy Verburg-van Kemenadeb ; Magdalena Chadzinskac
- 关键词：Hypothalamus-pituitary-gonad axis ; Immunity ; Reproduction ; Neuroendocrine ; Evolution ; Vertebrate ; Life history ; Trade-off
- 刊名：Developmental & Comparative Immunology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：66
- 期：Complete
- 页码：43-60
- 全文大小：741 K
文摘
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The hpyothalamic-pituitary-gonad (HPG) axis and the immune system of vertebrates communicate bidirectionally.
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The HPG-immune interaction is one among several proximate mechanisms mediating the life history trade-offs between reproduction and immunity of vertebrates.
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The HPG-immune interaction is evolutionary conserved.