Pu-erh ripened tea resists to hyperuricemia through xanthine oxidase and renal urate transporters in hyperuricemic mice

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• 作者：Ran Zhao^a ; ^b ; ^c ; ^{250424005@qq.com} ; Dong Chen^b ; ^c ; ^{chendong1113@sohu.com} ; Hualing Wu^b ; ^c ; ^{wuhualing@163.com}
• 关键词：Pu-erh ripened tea ; Hyperuricemia ; Uric acid ; Xanthine oxidase ; Urate transporters
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：29
• 期：Complete
• 页码：201-207
• 全文大小：1162 K
• 卷排序：29

文摘

Pu-erh ripened tea has the effects of reducing uric acid levels in serum. The tea inhibits xanthine oxidase and adenosine deaminase activities in liver. The tea down-regulates renal mGLUT9 and mURAT1 protein and mRNA expression. Its mechanisms are inhibiting uric acid production and renal urate reabsorption.