Residues of 2-hydroxy-3-phenylpyrazine, a degradation product of some β-lactam antibiotics, in environmental water in Vietnam

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• 作者：Nguyen Van Sy^a ; ^b ; Kazuo Harada^a ; ^{harada6@phs.osaka-u.ac.jp} ; Megumi Asayama^a ; Minae Warisaya^a ; Le Hong Dung^b ; Yoshinori Sumimura^c ; Khong Thi Diep^d ; Le Viet Ha^d ; Nguyen Nam Thang^d ; Tran Thi Tuyet Hoa^e ; Tran Minh Phu^e ; Pham Ngoc Khai^d ; Nguyen Thanh Phuong^e ; Le Danh Tuyen^b ; Yoshimasa Yamamoto^a ; ^f ; Kazumasa Hirata^a
• 关键词：Ampicillin ; Degradation products ; Environmental water ; 2-Hydroxy-3-phenylpyrazine ; Liquid chromatography/tandem mass spectrometry
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：172
• 期：Complete
• 页码：355-362
• 全文大小：1265 K
• 卷排序：172

文摘

A method to detect 2-hydroxy-3-phenylpyrazine was validated with LC/MS/MS. HPP residues were detected in 61% of samples, ranging from 1.3 to 413.3 ng L−1. Residue levels in rivers in city centres were higher than those in other sites. No sample from aquacultural ponds was found to contain HPP residue.