Tetanus toxin production is triggered by the transition from amino acid consumption to peptides
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- 作者：Cuauhtemoc Licona-Cassania ; c ; 1 ; Jennifer A. Steena ; 1 ; Nicolas E. Zaragozaa ; Glenn Moonenb ; George Moutafisb ; Mark P. Hodsona ; d ; John Powerb ; Lars K. Nielsena ; Esteban Marcellina ; e.marcellin@uq.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Clostridium tetani ; Fermentation maps ; Systems biology ; TeTN production
- 刊名：Anaerobe
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：41
- 期：Complete
- 页码：113-124
- 全文大小：2242 K
文摘
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High resolution transcriptomics and metabolomics map in pathogenic clostridia mimicking an industrial process.
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Exponential growth is characterised by the consumption of amino acids in Clostridium tetani.
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225">Toxin production is triggered at the transcriptional level by a nutritional switch – from amino acids to peptide consumption.