Determination of β-hydroxy-β-methylbutyrate concentration and enrichment in human plasma using chemical ionization gas chromatography tandem mass spectrometry

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• 作者：Dillon K. Walker ; ^{dk.walker@tamu.edu} ; John J. Thaden ^{jj.thaden@ctral.org} ; Agata Wierzchowska-McNew ^{a.wierzchowska@ctral.org} ; Marielle P.K.J. Engelen ^{mpkj.engelen@ctral.org} ; Nicolaas E.P. Deutz ^{nep.deutz@ctral.org}
• 关键词：HMB ; Chemical ionization ; Gas chromatography ; Tandem mass spectrometry ; Turnover
• 刊名：Journal of Chromatography B
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：1040
• 期：Complete
• 页码：233-238
• 全文大小：1173 K
• 卷排序：1040

文摘

HMB-Pentafluorobenzyl bromide derivative increases sensitive in GC/MS/MS. Tandem mass spectrometer improves HMB measurement sensitivity. HMB turnover in humans is 0.66 umol/kg ffm/h.