Diazo ester insertion in NH bonds of amino acid derivatives and insulin catalyzed by water-soluble iron and ruthenium porphyrin complexes (FeTSPPCl) as application of carbenoid transfer in aqueous media
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- 作者：Hassan F. Sroura ; Paul Le Mauxa ; Soizic Chevancea ; Daniel Carrié ; a ; Nicolas Le Yondreb ; Gé ; rard Simonneauxa ; gerard.simonneaux@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Catalytic NH insertion ; Iron porphyrin ; Diazo ester ; Amino ester ; Insulin
- 刊名：Journal of Molecular Catalysis A: Chemical
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：407
- 期：Complete
- 页码：194-203
- 全文大小：1421 K
文摘
- •
We report diazo ester insertion in N
H bonds of amino acid derivatives.- •
Sulfonated iron porphyrin is an active catalyst for carbenoid insertion in N
H bonds of aminoacid derivatives in aqueous media.- •
Insertion is regioselective onto the NH2 termini of chain B of insulin.