Steroid modulation of neurogenesis: Focus on radial glial cells in zebrafish
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- 作者：Elisabeth Pellegrinia ; elisabeth.pellegrini@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author ; Nicolas Diotela ; b ; c ; Colette Vaillant-Capitainea ; Rita Pé ; rez Mariaa ; d ; Marie-Madeleine Gueguena ; Ahmed Nasria ; e ; Joel Cano Nicolaua ; Olivier Kaha
- 关键词：Zebrafish ; Radial glial progenitor cells ; Neurosteroids ; Aromatase ; Estradiol ; Endocrine disruptors
- 刊名：Journal of Steroid Biochemistry and Molecular Biology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：160
- 期：Complete
- 页码：27-36
- 全文大小：1803 K
文摘
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The brain of adult zebrafish is a source of steroids and target of steroids.
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Aromatase expression is restricted to radial glial cells in the adult zebrafish.
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Radial glial cells are progenitor cells in the brain of adult zebrafish.
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Estradiol negatively regulates the proliferation and the migration of newborn cells.
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Aromatase expression is induced in parenchymal cells after mechanical injury.