Circulating microRNAs and hypertension ‿from new insights into blood pressure regulation to biomarkers of cardiovascular risk
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- 作者：Simon PR Romaine1 ; 2 ; Fadi J Charchar3 ; Nilesh J Samani1 ; 2 ; Maciej Tomaszewski4 ; maciej.tomaszewski@manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Opinion in Pharmacology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：27
- 期：Complete
- 页码：1-7
- 全文大小：472 K
文摘
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MicroRNAs have highlighted new regulatory aspects of blood pressure control.
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Array-based studies identified many microRNAs that are dysregulated in hypertension.
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Circulating microRNAs are excellent candidate biomarkers in hypertension.
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MicroRNA biomarkers of target-organ damage show the greatest potential.
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Technical challenges remain before microRNA biomarkers can enter clinical practice.