Intracellular haemolytic agents of Heterocapsa circularisquama exhibit toxic effects on H. circularisquama cells themselves and suppress both cell-mediated haemolytic activity and toxicity to rotifers (Brachionus plicatilis)
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A harmful dinoflagellate Heterocapsa circularisquama has light-dependent and -independent haemolytic agents.

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The light-independent haemolytic agents located on the cell surface may be mainly responsible for the toxic action.

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The ruptured cells can suppress the live cell-mediated light-independent haemolytic activity and toxicity to rotifer.

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The light-dependent haemolytic agents discharged from the ruptured cells may contain porphyrin derivatives with suppressive effect on the toxic action.

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Physical destruction of Heterocapsa circularisquama can lead to mitigation of various harmful algae species.

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