Regulatory mechanism of the flavoprotein Tah18-dependent nitric oxide synthesis and cell death in yeast
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- 作者：Yuki Yoshikawa1 ; Ryo Nasuno1 ; Nobuhiro Kawahara ; Akira Nishimura ; Daisuke Watanabe ; Hiroshi Takagi ; hiro@bs.naist.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Yeast ; Saccharomyces cerevisiae ; Nitric oxide ; Tah18 ; Dre2 ; Nitric oxide synthase ; Cell death
- 刊名：Nitric Oxide
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：57
- 期：Complete
- 页码：85-91
- 全文大小：910 K
文摘
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The regulatory mechanism of NO synthesis and cell death was analyzed in yeast.
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The Tah18-Dre2 complex dissociates after exposure to H2O2.
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Enhanced interaction between Tah18 and Dre2 suppressed NO synthesis and cell death.
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The Tah18-Dre2 complex regulates cell death via Tah18-dependent NO production.