Single-energy metal artifact reduction in postimplant computed tomography for I-125 prostate brachytherapy: Impact on seed identification

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• 作者：Yutaka Shiraishi ; ^{shiraishi@rad.med.keio.ac.jp} ; Yoshitake Yamada ; ^{yamada@rad.med.keio.ac.jp} ; Tomoki Tanaka ; Takahisa Eriguchi ; Shuichi Nishimura ; Kayo Yoshida ; Takashi Hanada ; Toshio Ohashi ; Naoyuki Shigematsu ; Masahiro Jinzaki
• 关键词：Brachytherapy ; I-125 ; Prostate ; Metal artifact reduction
• 刊名：Brachytherapy
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：15
• 期：6
• 页码：768-773
• 全文大小：438 K
• 卷排序：15

文摘

To evaluate the effectiveness of the single-energy metal artifact reduction (SEMAR) technique for improving the accuracy of I-125 seed identification in postimplant computed tomography (CT) after prostate brachytherapy.Methods and MaterialsPostimplant CT images of 40 patients treated with I-125 prostate brachytherapy were acquired. For all patients, 2 data sets were reconstructed, 1 with SEMAR algorithms (SEMAR image), and the other without SEMAR algorithms (non-SEMAR image). Seed locations are automatically detected by the automatic seed finder tool, and their locations were compared between the SEMAR and non-SEMAR images. Dosimetric parameters using seed locations as detected were compared.ResultsThe true-positive fraction of properly detected seeds on the SEMAR image as determined from a reference seed distribution defined by one investigator was significantly higher than the true-positive fraction on the non-SEMAR image (p = 0.011). The variabilities in D90 (p = 0.001), V100 (p = 0.007), and V150 (p = 0.007) were significantly reduced for seed location on the SEMAR image as compared with non-SEMAR image.ConclusionsProstate postimplant CT with SEMAR improved the accuracy of seed localization and postimplant dosimetric parameters.