S-Nitrosothiols—NO donors regulating cardiovascular cell proliferation: Insight into intracellular pathway alterations
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- 作者：Marek Rychtera ; Caroline Gaucherb ; Ariane Boudierb ; Pierre Leroyb ; Janina Luleka ; jlulek@ump.edu.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：EDRF ; endothelium-derived relaxing factor ; sGC ; soluble guanylate cyclase ; cGMP ; cyclic guanosine monophosphate ; RSNO ; S-nitrosothiol ; GSNO ; S-nitrosoglutathione ; PTM ; post-translational modifications ; NOS ; nitric oxide synthase ; GTP ; guanosine triphospate ; cGMP ; cyclic guanosine monophosphate ; VSMC ; vascular smooth muscle cells ; ACh ; acetylcholine ; VEGF ; vascular endothelial growth factor ; BDK ; bradykinin ; eNOS ; endothelial nitric oxide synthase ; PRT ; protein ; Trx ; thioredoxin ; VASP ; vasodilato
- 刊名：International Journal of Biochemistry and Cell Biology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：156-161
- 全文大小：919 K
文摘
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cGMP dependent and independent mechanism of NO based signaling pathways modulates vascular cell proliferation
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cGMP independent mechanism occurs through cysteine S-nitrosation and S-glutathionylation, tyrosine nitration of proteins.
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Further insight into NO based signaling pathway can be found at http://www.sfrbm.org/sections/education/frs-presentations.