Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in mice
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- 作者：G.C. Sartor1 ; S.K. Powell1 ; H.J. Wiedner ; C. Wahlestedt ; S.P. Brothers ; sbrothers@med.miami.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cocaine ; Nociceptin ; Conditioned place preference
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：1632
- 期：Complete
- 页码：34-41
- 全文大小：566 K
文摘
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We tested the selective NOP agonist, SR8993, in cocaine reward-related behaviors.
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SR8993 failed to attenuate cocaine CPP acquisition, expression and reinstatement.
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Selective activation of NOP may not be sufficient in reducing cocaine reward.