Pharmacological characterization of the nociceptin/orphanin FQ receptor on ethanol-mediated motivational effects in infant and adolescent rats
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- 作者：Roberto Sebastiá ; n Miranda-Moralesa ; smiranda@immf.uncor.edu" class="auth_mail" title="E-mail the corresponding author ; Ricardo M. Pautassia ; b
- 关键词：Ethanol anxiolytic effect ; Ethanol-induced locomotor activation ; Early ontogeny ; NOP opioid receptor
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：298
- 期：part_PA
- 页码：88-96
- 全文大小：1109 K
文摘
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Infant and adolescent rats are sensitive to ethanol's reinforcing properties.
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Activation of NOP receptors did not alter ethanol-induced CTA.
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Activation of NOP receptors did not alter ethanol intake patterns in adolescents.
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Activation of NOP receptors attenuated ethanol-induced anxiolysis in adolescents.
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Activation of NOP receptors inhibited ethanol's stimulating effects in adolescents.