An enantiospecific synthesis of a komarovispirane
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- 作者：Adusumilli Srikrishna ; B. Beeraiah
- 关键词：Indol-2-yl quinoline-2-one ; Synthesis ; 5-endo-dig-Cyclization ; KDR kinase inhibitor
- 刊名：Tetrahedron: Asymmetry
- 出版年：2007
- 出版时间：22 October 2007
- 年：2007
- 卷：18
- 期：21
- 页码：2587-2597
- 全文大小：369 K
文摘
The enantiospecific total synthesis of a komarovispirane, containing the complete carbon framework, trans-bicyclo[4.3.0]nonanespiro[8.1′]cyclohexane, of the spiroditerpene komarovispirone, starting from the readily available campholenaldehyde is described.