Status epilepticus caused by cerebral amyloid angiopathy-related inflammation

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• 作者：Benjamin Tolchin^a ; ^{btolchin@partners.org" class="auth_mail" title="E-mail the corresponding author} ; Tadeau Fantaneanu^a ; Michael Miller^b ; Jeffrey Helgager^b ; Jong Woo Lee^a
• 关键词：Cerebral amyloid angiopathy ; Inflammation ; Status epilepticus ; MRI ; EEG ; Pathology
• 刊名：Epilepsy & Behavior Case Reports
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：6
• 期：Complete
• 页码：19-22
• 全文大小：1169 K

文摘

This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating inflammatory process. Immunomodulatory treatment with pulse steroids resulted in rapid and dramatic clinical and radiographic improvement. Cerebral amyloid angiopathy-related inflammation should be considered in the differential diagnosis of new-onset seizures after the age of 40, when associated with fluctuating multifocal T2 hyperintensities and petechial hemorrhages on gradient echo (GRE) or susceptibility-weighted (SWI) MRI sequences.