- 作者：Carolina Ferreira Nicoletti ; Marcia Varella Mor ; i Junqueira-Franco ; Jose Ernesto dos Santos ; Julio Sergio Marchini ; Wilson Salgado Junior ; Carla Barbosa Nonino
- 关键词：Obesity ; Bariatric surgery ; Amino acids ; Albumin protein
- 刊名：Surgery for Obesity and Related Diseases
- 出版年：November-December, 2013
- 年：2013
- 卷：9
- 期：6
- 页码：1008-1012
- 全文大小：193 K
Background
Patients with obesity submitted to bariatric surgery present altered ingestion of macronutrient and micronutrient levels and nutrients deficiency. The objective of this study was to evaluate the protein and amino acid nutritional status of obese adults before and after bariatric surgery, with emphasis on plasma free amino acids.Methods
Thirty obese women were submitted to Roux-en-Y gastric shunt (bariatric surgery). Food and protein intake, anthropometric and bioimpedance data (body composition analysis), and serum total protein, albumin, and plasma amino acids levels were collected before the surgery (preoperative) and 3, 6, and 12 months after the surgical procedure.
Results
The mean protein intake was 47卤2 g/day. The total weight loss during the study period was 39卤8 kg; the fat-free mass decreased 7卤5 kg. The amino acid profile showed increased concentrations of most amino acids 3 months after surgery; at 6 months, glutamic acid, serine, arginine, alanine, methionine, valine, phenylalanine, isoleucine, and tyrosine concentrations decreased. The total protein and albumin concentrations dropped along the 12-month follow-up.
Conclusion
The amino acid profile changes after RYGB are evidence that total protein and albumin levels may not be good indicators of protein profile after the surgery.