- 作者：Simara Paganini Donadelli ; R.D.a ; Má ; rcia Varella Morandi Junqueira-Franco ; Ph.D.a ; Carlos Augusto de Mattos Donadelli ; M.D.b ; Wilson Salgado Jr. ; Ph.D.b ; Reginaldo Ceneviva ; Ph.D.b ; Jú ; lio Sé ; rgio Marchini ; Ph.D.a ; José ; Ernesto Dos Santos ; Ph.D.a ; Carla Barbosa Nonino ; Ph.D.a ; carla@fmrp.usp.br
- 关键词：Obesity ; Obesity surgery ; Gastric bypass ; Vitamins ; Nutritional deficiencies
- 刊名：Nutrition
- 出版年：2012
- 出版时间：April, 2012
- 年：2012
- 卷：28
- 期：4
- 页码：391-396
- 全文大小：213 K
Objective
The objective of this study was to determine whether constant daily vitamin supplementation would be sufficient to prevent possible vitamin deficiencies in obese patients undergoing bariatric surgery.Methods
The study was conducted on 58 men and women (mean age 41 ¡À 10 y) who underwent Roux-en-Y gastric bypass RYGB and were assessed preoperatively and at 3, 6, and 12 mo after surgery. During the postoperative period, the patients received a multivitamin-mineral supplement on a daily basis.
Results
Serum ¦Â-carotene and vitamin C were lower starting from the third postoperative month and continued to be low after 12 mo, and vitamin A was decreased by the sixth month and increased by 12 mo. Vitamin B12 levels were stable up to 6 mo but were decreased by 12 mo. Folic acid levels increased from the third month and remained higher throughout follow-up. One year after surgery there were 19 % and 21 % increases in the number of patients with vitamin A and vitamin C deficiency, respectively, and a 4 % decreased of patients with folic acid deficiency.
Conclusion
Weight loss and improvement in patients?general condition followed surgery, but serum levels of some vitamins were decreased despite the use of a vitamin-mineral supplement. These patients need continuous follow-up and individualized prescription of supplementation after the surgical procedure to prevent and treat vitamin deficiencies.