Dominant nonsense mutations Q64X and Q344X do not induce NMD.
Recessive nonsense mutations W161X, and E249X induce NMD.
Dominant nonsense mutation Y136X, which has a mild phenotype, induces NMD.
Wortmannin treatment, which inhibits NMD, eliminates Y136X, W161X, and E249X mRNA degradation.
Inheritance patterns for rhodopsin nonsense mutations correlate with induction of NMD.