Endosulfan decreases cytotoxic activity of nonspecific cytotoxic cells and expression of granzyme gene in Oreochromis niloticus
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- 作者：Martha Cecilia Té ; llez-Bañ ; uelosa ; ceciliat@prodigy.net.mx" class="auth_mail ; Pablo Cesar Ortiz-Lazarenob ; Luis Felipe Jave-Suá ; rezb ; Victor Hugo Siordia-Sá ; ncheza ; Alejandro Bravo-Cuellarb ; Anne Santerrea ; Galina P. Zaitsevaa
- 关键词：Endosulfan ; Nile tilapia ; NCC ; Cytotoxic activity ; Granzyme
- 刊名：Fish & Shellfish Immunology
- 出版年：May 2014
- 年：2014
- 卷：38
- 期：1
- 页码：196-203
- 全文大小：1321 K
文摘
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Endosulfan affects the innate cellular immune response of Nile tilapia.
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Endosulfan decreases cytotoxic activity of NCC in tilapia.
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NCC were identified with Mab 5C6 for the NCCRP-1.
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NCC cytotoxicity was evaluated using flow cytometry, and granzyme expression was examined by RT-PCR.