Prefrontal disturbances as the sole manifestation of simple partial nonconvulsive status epilepticus

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• 作者：Gerhard Bauer ; Judith Dobesberger ; Richard Bauer ; Norbert Embacher ; Thomas Benke ; Iris Unterberger ; Gerald Walser ; Gerhard Luef and Eugen Trinka
• 关键词：Frontal lobe epilepsy ; Nonconvulsive status epilepticus ; Prefrontal signs
• 刊名：Epilepsy & Behavior
• 出版年：2006
• 出版时间：February 2006
• 年：2006
• 卷：8
• 期：1
• 页码：331-335
• 全文大小：339 K

文摘

We describe a case of frontal lobe epilepsy with rare nocturnal generalized tonic–clonic seizures and repeated prolonged episodes of altered behavior lasting 1 to 2 days. The changes consisted of poor organizational strategies, impaired set shifting, emotional indifference, reduced motivation, and impairment of emotional decision making. Memory and consciousness were undisturbed, as she was able to follow her profession as a teacher. During the episode, the EEG was marked by right frontal rhythmical spikes and waves with spread to the homologous left region. Behavioral abnormalities and EEG changes were successfully treated with intravenous diazepam. The clinical representation can be ascribed to alterations of prefrontal-subcortical circuits, especially the anterior cingulate and orbitofrontal circuits. This unique case is classified as simple partial nonconvulsive status epilepticus with prefrontal disturbances as the sole manifestation.