Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
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- 作者：Katrine L. Rasmussena ; e ; katrine.laura.rasmussen@regionh.dk" class="auth_mail" title="E-mail the corresponding author ; Anne Tybjæ ; rg-Hansena ; b ; c ; e ; anne.tybjaerg.hansen@regionh.dk" class="auth_mail" title="E-mail the corresponding author ; Bø ; rge G. Nordestgaardb ; c ; d ; e ; boerge.nordestgaard@regionh.dk" class="auth_mail" title="E-mail the corresponding author ; Ruth Frikke-Schmidta ; c ; e ; ruth.frikke-schmidt@regionh.dk" class="auth_mail" title="E-mail the corresponding author
- 关键词：APOE ; Apolipoprotein E ; Genetics ; HDL ; Ischemic heart disease ; Myocardial infarction ; Triglycerides
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：246
- 期：Complete
- 页码：63-70
- 全文大小：1393 K
文摘
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High plasma apoE was associated with increased risk of IHD in men but not in women.
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The associations were independent of APOE genotype.
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The associations were attenuated after adjustment for triglycerides.
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Triglyceride-rich lipoproteins may partly explain these associations.