Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development
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- 作者：Pawel Durek1 ; 23 ; Karl Nordströ ; m2 ; 23 ; Gilles Gasparoni2 ; 23 ; Abdulrahman Salhab2 ; 23 ; Christopher Kressler1 ; 23 ; Melanie de Almeida1 ; 23 ; Kevin Bassler3 ; Thomas Ulas3 ; Florian Schmidt4 ; 5 ; Jieyi Xiong6 ; Petar Glažar7 ; Filippos Klironomos7 ; Anupam Sinha8 ; Sarah Kinkley9 ; Xinyi Yang9 ; Laura Arrigoni10 ; Azim Dehghani Amirabad4 ; 5 ; Fatemeh Behjati Ardakani4 ; 5 ; Lars Feuerbach11 ; Oliver Gorka12 ; Peter Ebert4 ; Fabian Mü ; ller4 ; Na Li9 ; Stefan Frischbutter1 ; Stephan Schlickeiser13 ; Carla Cendon14 ; Sebastian Frö ; hler6 ; Bä ; rbel Felder15 ; Nina Gasparoni2 ; Charles D. Imbusch11 ; Barbara Hutter11 ; Gideon Zipprich15 ; Yvonne Tauchmann16 ; Simon Reinke17 ; Georgi Wassilew18 ; Ute Hoffmann1 ; Andreas S. Richter10 ; Lina Sieverling11 ; DEEP Consortium19
- 刊名：Immunity
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：45
- 期：5
- 页码：1148-1161
- 全文大小：13584 K
文摘
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Comprehensive epigenomes for human CD4+ T memory subsets generated and analyzed
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Integrative analyses support a linear model of memory T cell differentiation
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Epigenetic control of transcriptional regulators of memory differentiation revealed
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Chromatin changes highlight novel regulators for T memory cell differentiation