¦Â-Carboline-type indole alkaloid glycosides from Ophiorrhiza trichocarpon

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• 作者：Mariko Kitajima ; Satoko Ohara ; Noriyuki Kogure ; Dammrong Santiarworn ; Hiromitsu Takayama
• 关键词：Alkaloid ; Indole ; Glycoside ; ¦Â-Carboline ; Ophiorrhiza ; Structure elucidation
• 刊名：Tetrahedron
• 出版年：2013
• 出版时间：11 November, 2013
• 年：2013
• 卷：69
• 期：45
• 页码：9451-9456
• 全文大小：623 K

文摘

Six new ¦Â-carboline-type indole alkaloid glycosides, ophiorrhisides A-F (1-6), were isolated from Ophiorrhiza trichocarpon (Rubiaceae) collected in Thailand. Ophiorrhisides A (1) and B (2) possess a lactam function in the C ring and a unique biose residue in the molecule. Ophiorrhiside F (6) has a highly oxidized C ring with a 1,2-dicarbonyl function at C-5 and C-6 positions as well as a double bond between C-3 and C-14.