The Effect of Urinary Incontinence on Health-related Quality of Life: Is It Similar in Men and Women?

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• 作者：Dina Bedretdinova^a ; ^b ; ^c ; ^d ; ^{dina.dinova@inserm.fr" class="auth_mail" title="E-mail the corresponding author} ; ^{dina.dinova@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Xavier Fritel^a ; ^d ; ^e ; Marie Zins^f ; Virginie Ringa^a ; ^d ; ^e
• 刊名：Urology
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：91
• 期：Complete
• 页码：83-89
• 全文大小：184 K

文摘

To compare the association between self-reported urinary incontinence (UI) and health-related quality of life (HRQoL) in men and women while taking chronic comorbidities into account, on the hypothesis that UI might negatively affect HRQoL differently in each sex.

Methods

In 2006, a total of 10,723 men (aged 57-67 years) and 3777 women (aged 52-67 years) participating in the GAZEL cohort (www.gazel.inserm.fr) completed a self-administered questionnaire including the Nottingham Health Profile to assess HRQoL. UI was defined as self-reported involuntary loss of urine in the past 12 months. Adjusted logistic regression models were fitted to estimate the association between impaired HRQoL and UI, taking age, chronic conditions, and other confounders into account. For each QoL dimension, we compared the strength of the associations between UI and HRQoL between the sexes by tests of interaction.

Results

Women were more likely than men to report both UI (13.9% vs 2.7%) and impaired HRQoL. UI was associated with impaired HRQoL in both sexes, mainly in the dimensions of energy (OR = 3.17 in men [95% CI 2.49-4.04] and 2.11 in women [1.75-2.54]), social isolation (OR = 2.29 in men [1.74-3.02] and 1.75 in women [1.44-2.12]), and physical mobility (OR = 2.05 in men [1.62-2.60] and 2.27 in women [1.88-2.74]). There were no significant interactions between the sexes after adjustment.

Conclusion

UI was associated negatively with HRQoL in both sexes, mostly in the dimensions of energy, social isolation, and physical mobility. The association was similar in men and women after we took age, sociodemographic characteristics, and chronic diseases into account. The cross-sectional design of the analysis prevents any conclusion that UI induced an impairment of HRQoL, and no causal relation can be inferred.