Biodegradation rates of NSAIDs in river/sediment systems depend on redox conditions. Biodegradation rate of NSAIDs are faster under aerobic than anaerobic conditions. Sorption is a rather insignificant process for removing NSAIDs from river water. Ibuprofen is removed from river water through biodegradation rather than sorption. Ibuprofen biodegraded faster than Naproxen, Diclofenac and Ketoprofen.