Radiosensitization of oral tongue squamous cell carcinoma by nanosecond pulsed electric fields (nsPEFs)
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- 作者：Jinsong Guoa ; Yu Wangb ; Jing Wangc ; lzukqwj@126.com" class="auth_mail" title="E-mail the corresponding author ; Jue Zhanga ; b ; zhangjue@pku.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jing Fanga ; b
- 关键词：Radiosensitization ; nsPEFs ; TSCC ; G2/M arrest ; Nitric oxide ; Apoptosis
- 刊名：Bioelectrochemistry
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：113
- 期：Complete
- 页码：35-41
- 全文大小：1341 K
文摘
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Nanosecond pulsed electric fields are a safe, non-thermal and non-toxic technology.
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NsPEFs had a time and strength dependent inhibition effect on Tca8113 cells.
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Radiation induced G2/M arrest was augmented by treatment with nsPEFs.
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Many more cells showing early apoptosis after nsPEFs combined with radiotherapy.
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The NO concentration was significantly increased after nsPEFs treatment.