The 91-205 amino acid region of AcMNPV ORF34 (Ac34), which comprises a potential C3H zinc finger, is required for its nuclear localization and optimal virus multiplication
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- 作者：Jianxiang Qiu ; Zhimin Tang ; Meijin Yuan ; Wenbi Wu ; wuwenbi3@mail.sysu.edu.cn ; Kai Yang
- 关键词：Baculovirus ; AcMNPV ; ac34 ; Nuclear localization
- 刊名：Virus Research
- 出版年：2017
- 出版时间：15 January 2017
- 年：2017
- 卷：228
- 期：Complete
- 页码：79-89
- 全文大小：2608 K
- 卷排序：228
文摘
The Autographa californica multiple nucleopolyhedrovirus Ac34 locates to the nucleus of Sf9 cells without the assistance of other viral proteins. The 91-205 amino acid region of Ac34 is required for its nuclear import. A potential C3H zinc finger located in amino acid 116-131 of Ac34 is essential for nuclear import. Nuclear localization of Ac34 is required for optimal virus replication.