Upregulation of HMGB1, toll-like receptor and RAGE in human Rasmussen’s encephalitis
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- 作者：Guoming Luana ; Qing Gaob ; Feng Zhaia ; Yin Chenb ; Tianfu Lib ; c ; tianfuli66@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：RE ; Rasmussen encephalitis ; HMGB1 ; high-mobility group box-1 ; RAGE ; receptor for advanced glycation end products ; TLR ; Toll-like receptor ; SPS ; simple partial seizure ; EPC ; epilepsia partialis continua ; CPS ; complex partial seizure ; GTCS ; generalized tonic clonic seizure ; EEG ; electroencephalography ; GFAP ; glial fibrillary acidic protein ; NeuN ; neuronal nuclear protein
- 刊名：Epilepsy Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：123
- 期：Complete
- 页码：36-49
- 全文大小：7756 K
文摘
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Activation of HMGB1/TLR signaling is proposed in epileptogenic mechanisms of RE.
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Nuclear to cytoplasm translocation of HMGB1 in reactive astrocyte in RE.
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Significant greater HMGB1 and its receptors expression in RE.